November 26, 2025
Europe/Bratislava timezone

Single-cell mutational burden distributions in birth–death processes

Nov 26, 2025, 3:21 PM
1m
Zamestnanci matematika Poster session + káva: prezentácie vedeckých výsledkov FMFI UK Zamestnanci Matematika Poster session + káva: prezentácie vedeckých výsledkov FMFI UK Zamestnanci Matematika

Description

We introduce a birth–death model of neutral tumour evolution uniting summary statistics via dynamical matrices. We derive and solve recurrence relations to find analytical expressions for expected mutational distributions. We compare to known results and simulated data, validating our predictions. (based on the paper: https://doi.org/10.1371/journal.pcbi.1013241)

Pracovisko fakulty (katedra)/ Department of Faculty KAMŠ
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