Description
Gene expression is inherently stochastic, resulting in cell-to-cell variability in protein levels, even among genetically identical cells.
Such variability plays a crucial role in such processes as cell differentiation, stress response, and antibiotic tolerance.
- Proteins are synthesized in instantaneous discrete events, bursts, each producing a random number of proteins.
- Protein levels are decreased by dilution due to active cell growth.
- Positive feedback on dilution: an increase in protein levels imposes a burden on the cell, reducing its growth rate and thereby slowing down dilution.
| Pracovisko fakulty (katedra)/ Department of Faculty | KAMŠ |
|---|---|
| Tlač postru/ Print poster | Nebudem požadovať tlač posteru / I don't require to print the poster |
Authors
Iryna Zabaikina
(Comenius university in Bratislava, FMFI)
Jakub Poljovka
(KAMŠ)
Pavol Bokes
(Comenius University Bratislava)
